In this project we intend to settle on the lipid droplet proteome of hepatic stellate cells. Lipid droplets will be isolated from the stable rat stellate cellline HSC-T6 and from primary murine hepatic stellate cells. Quiescent and activated stellate cells will be attained in culture or isolated from mice. Determination of the lipid droplet proteome will allow us to recognize potential lipid hydrolases which will be cloned and studied in vitro and in cell experiments.
We are looking for a highly motivated apprentice, student with a background in molecular biology and biochemistry and interest in mammalian physiology. Knowledge and experience in handling of laboratory animals and in performing cell experiments is desirable.
The research group is situated at the Institute of Molecular Biosciences at the University of Graz, which locates a number of globally competitive and renowned research groups. The project will engage national and international collaborations. The laboratory offers a multi-disciplinary, young and supportive research environment with an international research profile. The PhD will be supported and funded for 3 years from a FWF funding according to FWF regulations.
The position is available from beginning January 2013. Applications should include a cover letter, motivation letter and a CV and should be sent to:
Application Deadline: 15 November 2012.